Daklinza is indicated in combination with other medicinal products for the treatment of chronic hepatitis C virus (HCV) infection in adults
For HCV genotype specific activity,
Adult Dosing .
Dosage forms: 30,60
hepatitis C infection, chronic
Dose: 60 mg PO qd x12wk; Info: screen for NS5A polymorphism in pts w/ genotype 1a; give w/ sofosbuvir; D/C tx if sofosbuvir D/C
Dose: 60 mg PO qd x12wk; Info: give w/ sofosbuvir; D/C tx if sofosbuvir D/C
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.
Contraindications / Cautions .
hypersens. to drug/class/compon.
Drug Interactions .
OATP1B1 inhibitor, weak
OATP1B3 inhibitor, weak
P-gp inhibitor, weak