Sterile Aqueous Suspension
Brand of betamethasone dipropionate and betamethasone sodium phosphate.
FOR INTRAMUSCULAR, INTRA-ARTICULAR, PERI-ARTICULAR,
INTRABURSAL, INTRADERMAL, INTRALESIONAL, AND SOFT TISSUE
DIPROSPAN Suspension is a sterile aqueous injectable suspension of betamethasone
dipropionate and betamethasone sodium phosphate. Each ml of DIPROSPAN Suspension
contains 5 mg of betamethasone as dipropionate and 2 mg of betamethasone as sodium
phosphate in a sterile buffered vehicle.
DIPROSPAN Sterile Aqueous Suspension provides a combination of highly soluble and
very slightly soluble esters of betamethasone that produce anti-inflammatory, antirheumatic
and anti-allergic effects. Prompt therapeutic activity is achieved by the soluble ester,
betamethasone sodium phosphate, which is quickly absorbed after injection. Sustained
activity is provided by betamethasone dipropionate, which is only slightly soluble and
becomes a repository for slow absorption, thereby controlling symptoms over a prolonged
period. The small crystal size of betamethasone dipropionate permits the use of a finegauge
needle (up to 26 g) for intradermal and intralesional administration.
INDICATIONS AND USAGE
DIPROSPAN Sterile Aqueous Suspension is indicated for the treatment of acute and
chronic corticosteroid-responsive disorders such as the following conditions:
Musculoskeletal and Soft Tissue Conditions:
Rheumatoid arthritis, osteoarthritis, bursitis, ankylosing spondylitis, epicondylitis,
radiculitis, coccydynia, torticollis, sciatica, lumbago, ganglion cyst, exostosis, fasciitis.
Chronic bronchial asthma (including adjunctive therapy for status asthmaticus), hay fever,
angioneurotic edema, allergic bronchitis, seasonal or perennial allergic rhinitis, drug
reactions, serum sickness, insect bites.
Atopic dermatitis (nummular eczema), neurodermatitis (circumscribed lichen simplex),
necrobiosis lipoidica diabeticorum, alopecia areata, discoid lupus erythematosus, psoriasis,
keloids, pemphigus, dermatitis herpetiformis, urticaria, hypertrophic lichen planus, contact
dermatitis, severe solar dermatitis, cystic acne.